Efficacy of sonohysterography and hysteroscopy for evaluation of endometrial lesions in tamoxifen treated patients: a systematic review

Objective: This review aims to evaluate the incidence of endometrial lesions in tamoxifen-treated breast cancer patients identified by hysteroscopy (HS) and sonohysterography (SIS) diagnostic accuracy two methods detect them. Methods: A systematic literature concerning role HS SIS for evaluation endometrium was performed. We searched MEDLINE (PubMed), EMBASE, Cochrane Central Register Controlled Trials, IBECS, BIOSIS, Web Science, SCOPUS, congress abstracts, Grey (Google Scholar; British Library). The search terms used were “hysteroscopy”, “hysterosonography”, “sonohysterography” combined with “tamoxifen”; 89 citations selected initial screening. Results: 28 studies included review. There 61 excluded because they articles (n = 9) or case report 5) non-English 8), had too little information full text 39). Similar between detection tamoxifen-related found. Conclusions: may represent a minimally invasive, simple, safe, well-tolerated cost-effective alternative HS, associated few contraindications no potential complications.